Marinol is a prescription medicine available in the usa. The generic name for Marinol is dronabinol, and it is a synthetic compound equal to normal THC. The distinction between THC and dronabinol is that the source is that THC occurs in crops, also dronabinol's source occurs in a lab or chemical mill.
To be able to steer clear of illegalities in the united states, Unimed Pharmaceuticals generates Marinol from pure dronabinol. Natual bud is illegal, therefore developing that to a medicine could be hopeless and have it scheduled by the DEA for this. From the 1980's, Unimed went via the FDA 3 stages of new drug approval. Usually, it takes 5 years normally, however for Unimed it just took two decades.
Marinol has been approved by the FDA originally for management of nausea and vomiting with cancer back in 1985. Finally Unimed received further endorsement in 1992 for management of AIDS wasting. This additional approval took just two small studies, 3 decades, and $5 million. A massive deal in the sphere of further applications.
Dronabinol is a challenging medicine to get to the bloodstream. It doesn't readily dissolve in water, therefore a good deal of it does not get consumed. The liver really believes dronabinol is a contaminant and requires some from the blood. The final result is simply 10-20 percent really reaches cannabinoid receptors.
Marinol takes about two to four hours to take effect. Unwanted effects of dronabinol include stress, confusion, sleepiness, dizziness, and mood fluctuations. Smoked marijuana happens in seconds. Most patients have these consequences, and many will also be able to continue therapy.
The National Cancer Institute funded lots of the research back from the 1970's on bud which contributed hugely to Unimed's FDA approval. Originally Marinol was classified by the DEA as a schedule II medication. Unimed subsequently managed to find the DEA to reschedule Marinol to Schedule III in 1999. This did two things. It made research a lot easier to achieve, and secondly it made it much easier for doctors to prescribe (less paperwork).
The price of Marinol is roughly $200 a month to treating AIDS wasting. This is what 80 percent of prescriptions are given out to and the remainder is for prevention of nausea in cancer chemo. Whether Marinol is less costly than natural bud for treating these ailments is all up for debate. Natural bud can deal with a number of symptoms and side effects in HIV sufferers, therefore it might avoid the need for a secondary medicine combined with Marinol.